Human Protease, Serine 2 (PRSS2) RTU ELISA Kit | PRSS2 rtu elisa kit

Human Protease, Serine 2 (PRSS2) ELISA Kit

Cat. Num. AAA4502057

• Gene Names: PRSS2; TRY2; TRY8; TRYP2
• Reactivity: Human
• Synonyms: Protease; Serine 2 (PRSS2); Human Protease; Serine 2 (PRSS2) ELISA Kit; TRY2; Trypsin 2; Serine Endopeptidases; Anionic trypsinogen; PRSS2 rtu elisa kit

• Reactivity: Human
• Sequence Length: 247

• Assay Type: Sandwich
• Samples: Serum, Plasma or Other Biological Fluids.
• Detection Range: 0.781-50ng/mL
• Sensitivity: 0.21ng/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for PRSS2 rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to PRSS2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to PRSS2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain PRSS2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of PRSS2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 4506147
• NCBI GeneID: 5645
• NCBI Accession #: NP_002761.1
• NCBI GenBank Nucleotide #: NM_002770.3
• UniProt Accession #: P07478
• Molecular Weight: 26,488 Da
• NCBI Official Full Name: trypsin-2 isoform 2 preproprotein
• NCBI Official Synonym Full Names: serine protease 2
• NCBI Official Symbol: PRSS2
• NCBI Official Synonym Symbols: TRY2; TRY8; TRYP2
• NCBI Protein Information: trypsin-2
• UniProt Protein Name: Trypsin-2
• Protein Family: Trypsin
• UniProt Gene Name: PRSS2
• UniProt Synonym Gene Names: TRY2; TRYP2

NCBI Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]

Uniprot Description

In the ileum, may be involved in defensin processing, including DEFA5.