Human Protease, Serine 2 (PRSS2) ELISA Kit | PRSS2 elisa kit

Human Protease, Serine 2 (PRSS2) ELISA Kit

Cat. Num. AAA455946

• Gene Names: PRSS2; TRY2; TRY8; TRYP2
• Reactivity: Human
• Synonyms: Protease; Serine 2 (PRSS2); Human Protease; Serine 2 (PRSS2) ELISA Kit; TRY2 Trypsin 2 Serine Endopeptidases Anionic trypsinogen; PRSS2 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of PRSS2. No significant cross-reactivity or interference between PRSS2 and analogues was observed.
• Sequence Length: 247

• Samples: human serum, plasma or other biological fluids
• Detection Range: 0.781-50ng/mL
• Sensitivity: <0.21ng/mL
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level PRSS2 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
• Inter-assay Precision: Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level PRSS2 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for PRSS2 elisa kit

Intended Uses: The kit is a sandwich enzyme immunoassay for the in vitro quantitative measurement of PRSS2 in human serum, plasma or other biological fluids.

NCBI and Uniprot Product Information

• NCBI GI #: 4506147
• NCBI GeneID: 5645
• NCBI Accession #: NP_002761.1
• NCBI GenBank Nucleotide #: NM_002770.3
• UniProt Accession #: P07478
• Molecular Weight: 26,488 Da
• NCBI Official Full Name: trypsin-2 isoform 2 preproprotein
• NCBI Official Synonym Full Names: protease, serine 2
• NCBI Official Symbol: PRSS2
• NCBI Official Synonym Symbols: TRY2; TRY8; TRYP2
• NCBI Protein Information: trypsin-2
• UniProt Protein Name: Trypsin-2
• Protein Family: Trypsin
• UniProt Gene Name: PRSS2
• UniProt Synonym Gene Names: TRY2; TRYP2

NCBI Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]

Uniprot Description

In the ileum, may be involved in defensin processing, including DEFA5.