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Typical Testing Data/Standard Curve (for reference only)

Human Protease, Serine 2 (PRSS2) ELISA Kit | PRSS2 elisa kit

Human Protease, Serine 2 (PRSS2) ELISA Kit

Gene Names
PRSS2; TRY2; TRY8; TRYP2
Reactivity
Human
Synonyms
Protease; Serine 2 (PRSS2); Human Protease; Serine 2 (PRSS2) ELISA Kit; TRY2; Trypsin 2; Serine Endopeptidases; Anionic trypsinogen; PRSS2 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of PRSS2. No significant cross-reactivity or interference between PRSS2 and analogues was observed.
Sequence Length
247
Samples
human serum, plasma and other biological fluids
Detection Range
0.78-50ng/mL
Sensitivity
<0.28ng/mL
Intra-assay Precision
Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level PRSS2 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
Inter-assay Precision
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level PRSS2 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
Preparation and Storage
The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for PRSS2 elisa kit
Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PRSS2 in human serum, plasma and other biological fluids.
Product Categories/Family for PRSS2 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
26,488 Da
NCBI Official Full Name
protease, serine, 2 (trypsin 2), isoform CRA_b
NCBI Official Synonym Full Names
protease, serine, 2 (trypsin 2)
NCBI Official Symbol
PRSS2
NCBI Official Synonym Symbols
TRY2; TRY8; TRYP2
NCBI Protein Information
trypsin-2
UniProt Protein Name
Trypsin-2
Protein Family
UniProt Gene Name
PRSS2
UniProt Synonym Gene Names
TRY2; TRYP2
UniProt Entry Name
TRY2_HUMAN

NCBI Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]

Uniprot Description

trypsin 2: In the ileum, may be involved in defensin processing, including DEFA5. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.4; Secreted; Protease; Cell adhesion; Extracellular matrix; Calcium-binding; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function: protein binding; serine-type endopeptidase activity; calcium ion binding

Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; positive regulation of cell adhesion; digestion; innate immune response; proteolysis; positive regulation of cell growth

Disease: Pancreatitis, Hereditary

Research Articles on PRSS2

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Product Notes

The Human PRSS2 prss2 (Catalog #AAA2023430) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2023430 ELISA Kit recognizes Human PRSS2. It is sometimes possible for the material contained within the vial of "Protease, Serine 2 (PRSS2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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