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Lass3 peptide

Lass3

Gene Names
CERS3; LASS3
Reactivity
Human
Applications
Western Blot
Synonyms
Lass3; LAG1 longevity assurance homolog 3; Lass3 peptide
Ordering
For Research Use Only!
Reactivity
Human
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Sequence Length
383
Applicable Applications for Lass3 peptide
Western Blot (WB)
Immunogen
Synthetic peptide derived from human LASS3 protein
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Related Product Information for Lass3 peptide
LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.
Product Categories/Family for Lass3 peptide

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,316 Da
NCBI Official Full Name
ceramide synthase 3
NCBI Official Synonym Full Names
ceramide synthase 3
NCBI Official Symbol
CERS3
NCBI Official Synonym Symbols
LASS3
NCBI Protein Information
ceramide synthase 3; LAG1 homolog, ceramide synthase 3; LAG1 longevity assurance homolog 3
UniProt Protein Name
Ceramide synthase 3
UniProt Gene Name
CERS3
UniProt Synonym Gene Names
LASS3; CerS3
UniProt Entry Name
CERS3_HUMAN

NCBI Description

This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

Uniprot Description

Function: May be involved in sphingolipid synthesis or its regulation

By similarity.

Subcellular location: Nucleus membrane; Multi-pass membrane protein

Potential.

Sequence similarities: Contains 1 homeobox DNA-binding domain.Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Research Articles on Lass3

Similar Products

Product Notes

The Lass3 cers3 (Catalog #AAA396437) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. The Lass3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lass3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Lass3 cers3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lass3, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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