Testing Data
(P-peptide-+)
PLD1 Antibody | anti-PLD1 antibody
PLD1 (Phospho-Ser561) Antibody
Gene Names
PLD1; CVDD
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Synonyms
PLD1; PLD1 (Phospho-Ser561) Antibody; Choline phosphatase 1; EC 3.1.4.4; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; anti-PLD1 antibody
Reactivity
Human, Mouse, Rat
Specificity
PLD1 (Phospho-Ser561) antibody detects endogenous levels of PLD1 only when phosphorylated at serine 561.
Purity/Purification
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1074
Applicable Applications for anti-PLD1 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:1000
IF: 1:100-1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human PLD1 around the phosphorylation site of serine 561 (K-F-SP-L-Y).
All Sites
Human: Ser561
Mouse: Ser561
Rat: Ser561
Mouse: Ser561
Rat: Ser561
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(P-peptide-+)
Testing Data
(P-peptide-+)
Immunohistochemistry (IHC)
(P-peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using PLD1 (Phospho-Ser561) antibody. Immunofluorescence analysis of HepG2 cells, using PLD1 (Phospho-Ser561) antibody.)
Immunohistochemistry (IHC)
(P-peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using PLD1 (Phospho-Ser561) antibody. Immunofluorescence analysis of HepG2 cells, using PLD1 (Phospho-Ser561) antibody.)
Product Categories/Family for anti-PLD1 antibody
References
Nicholas Lehman, Blood, Nov 2006; 108: 3564-3572. Yoe-Sik Bae, J. Immunol., Apr 2000; 164: 4089. Maria Zeniou-Meyer, J. Biol. Chem., Jul 2007; 282: 21746-21757.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
112,184 Da
NCBI Official Full Name
phospholipase D1 isoform a
NCBI Official Synonym Full Names
phospholipase D1
NCBI Official Symbol
PLD1
NCBI Official Synonym Symbols
CVDD
NCBI Protein Information
phospholipase D1
UniProt Protein Name
Phospholipase D1
Protein Family
UniProt Gene Name
PLD1
UniProt Synonym Gene Names
PLD 1; hPLD1
NCBI Description
This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]
Uniprot Description
Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic ().
Research Articles on PLD1
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Product Notes
The PLD1 pld1 (Catalog #AAA8503862) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PLD1 (Phospho-Ser561) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLD1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the PLD1 pld1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLD1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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