Testing Data
PAR4 Antibody | anti-PAR4 antibody
PAR4 Antibody
Gene Names
F2RL3; PAR4
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PAR4; PAR4 Antibody; coagulation factor II (thrombin) receptor-like 3; coagulation factor II receptor-like 3; F2RL3; PAR-4; protease-activated receptor-4; proteinase-activated receptor 4; thrombin receptor-like 3; anti-PAR4 antibody
Reactivity
Human, Mouse, Rat
Specificity
PAR4 antibody detects endogenous levels of total PAR4 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
385
Applicable Applications for anti-PAR4 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:10000
IF: 1:100~1:500
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PAR4.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
Testing Data
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from HeLa cells, Jurkat cells and HepG2 cells, using PAR4 antibody. Immunofluorescence analysis of LOVO cells, using PAR4 antibody.)
Western Blot (WB)
(Peptide-+ Western blot analysis of extracts from HeLa cells, Jurkat cells and HepG2 cells, using PAR4 antibody. Immunofluorescence analysis of LOVO cells, using PAR4 antibody.)
Product Categories/Family for anti-PAR4 antibody
References
Kahn M.L., J. Biol. Chem. 273:23290-23296(1998). Kahn M.L., Nature 394:690-694(1998). Xu W.-F., Proc. Natl. Acad. Sci. U.S.A. 95:6642-6646(1998).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,133 Da
NCBI Official Full Name
proteinase-activated receptor 4 preproprotein
NCBI Official Synonym Full Names
F2R like thrombin or trypsin receptor 3
NCBI Official Symbol
F2RL3
NCBI Official Synonym Symbols
PAR4
NCBI Protein Information
proteinase-activated receptor 4
UniProt Protein Name
Proteinase-activated receptor 4
UniProt Gene Name
F2RL3
UniProt Synonym Gene Names
PAR4; PAR-4
NCBI Description
This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]
Uniprot Description
Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Research Articles on PAR4
Similar Products
Product Notes
The PAR4 f2rl3 (Catalog #AAA852160) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PAR4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PAR4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000. Researchers should empirically determine the suitability of the PAR4 f2rl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAR4, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
