Testing Data
(Peptide-+)
JIP2 Antibody | anti-JIP2 antibody
JIP2 Antibody
Gene Names
MAPK8IP2; IB2; IB-2; JIP2; PRKM8IPL
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
JIP2; JIP2 Antibody; C-jun-amino-terminal kinase-interacting protein 2; JNK-interacting protein 2; JIP-2; JNK MAP kinase scaffold protein 2; Islet-brain-2; IB-2; Mitogen-activated protein kinase 8-interacting protein 2; MAPK8IP2; IB2; PRKM8IPL; anti-JIP2 antibody
Reactivity
Human, Mouse, Rat
Specificity
JIP2 antibody detects endogenous levels of total JIP2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
824
Applicable Applications for anti-JIP2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human JIP2.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using JIP2 antibody. Western blot analysis of extracts from mouse brain cells, using JIP2 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using JIP2 antibody. Western blot analysis of extracts from mouse brain cells, using JIP2 antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HeLa cells, using JIP2 antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HeLa cells, using JIP2 antibody.)
Product Categories/Family for anti-JIP2 antibody
References
Yasuda J., Mol. Cell. Biol. 19:7245-7254(1999). Negri S., Genomics 64:324-330(2000). Dunham I., Nature 402:489-495(1999).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,070 Da
NCBI Official Full Name
C-Jun-amino-terminal kinase-interacting protein 2
NCBI Official Synonym Full Names
mitogen-activated protein kinase 8 interacting protein 2
NCBI Official Symbol
MAPK8IP2
NCBI Official Synonym Symbols
IB2; IB-2; JIP2; PRKM8IPL
NCBI Protein Information
C-Jun-amino-terminal kinase-interacting protein 2
UniProt Protein Name
C-Jun-amino-terminal kinase-interacting protein 2
UniProt Gene Name
MAPK8IP2
UniProt Synonym Gene Names
IB2; JIP2; PRKM8IPL; JIP-2; JNK-interacting protein 2; IB-2
NCBI Description
This gene encodes a scaffold protein that is thought to be involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. This protein has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases. [provided by RefSeq, Jun 2017]
Uniprot Description
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins ().
Research Articles on JIP2
Similar Products
Product Notes
The JIP2 mapk8ip2 (Catalog #AAA852917) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The JIP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JIP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000. Researchers should empirically determine the suitability of the JIP2 mapk8ip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JIP2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
