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Western Blot (WB) (Western blot analysis of extracts from 562 cells, using FOXE3 antibody.)

FOXE3 Antibody | anti-FOXE3 antibody

FOXE3 Antibody

Gene Names
FOXE3; AAT11; ASGD2; FKHL12; FREAC8; CTRCT34
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
FOXE3; FOXE3 Antibody; Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FKHL12; FREAC8; anti-FOXE3 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
FOXE3 antibody detects endogenous levels of total FOXE3 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
319
Applicable Applications for anti-FOXE3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human FOXE3.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from 562 cells, using FOXE3 antibody.)

Western Blot (WB) (Western blot analysis of extracts from 562 cells, using FOXE3 antibody.)
References
Semina E.V., Hum. Mol. Genet. 10:231-236(2001). Gregory S.G., Nature 441:315-321(2006). Larsson C., Genomics 30:464-469(1995).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,234 Da
NCBI Official Full Name
forkhead box protein E3
NCBI Official Synonym Full Names
forkhead box E3
NCBI Official Symbol
FOXE3
NCBI Official Synonym Symbols
AAT11; ASGD2; FKHL12; FREAC8; CTRCT34
NCBI Protein Information
forkhead box protein E3
UniProt Protein Name
Forkhead box protein E3
Protein Family
UniProt Gene Name
FOXE3
UniProt Synonym Gene Names
FKHL12; FREAC8; FREAC-8

NCBI Description

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009]

Uniprot Description

Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149).

Research Articles on FOXE3

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Product Notes

The FOXE3 foxe3 (Catalog #AAA852069) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The FOXE3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FOXE3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:1000. Researchers should empirically determine the suitability of the FOXE3 foxe3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXE3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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