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Western Blot (WB) (Western blot analysis of extracts from MCF-7 cells, using CA12 antibody.)

CA12 Antibody | anti-CA12 antibody

CA12 Antibody

Gene Names
CA12; CAXII; CA-XII; T18816; HsT18816
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CA12; CA12 Antibody; CA-XII; CAH12; carbonate dehydratase XII; carbonic anhydrase 12; CAXII; EC 4.2.1.1; anti-CA12 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
CA12 antibody detects endogenous levels of total CA12 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
354
Applicable Applications for anti-CA12 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CA12.

Western Blot (WB)

(Western blot analysis of extracts from MCF-7 cells, using CA12 antibody.)

Western Blot (WB) (Western blot analysis of extracts from MCF-7 cells, using CA12 antibody.)
References
Tuereci O., Proc. Natl. Acad. Sci. U.S.A. 95:7608-7613(1998). Ivanov S.V., Proc. Natl. Acad. Sci. U.S.A. 95:12596-12601(1998). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
771
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,408 Da
NCBI Official Full Name
carbonic anhydrase 12 isoform 1
NCBI Official Synonym Full Names
carbonic anhydrase 12
NCBI Official Symbol
CA12
NCBI Official Synonym Symbols
CAXII; CA-XII; T18816; HsT18816
NCBI Protein Information
carbonic anhydrase 12
UniProt Protein Name
Carbonic anhydrase 12
Protein Family
UniProt Gene Name
CA12
UniProt Synonym Gene Names
CA-XII

NCBI Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]

Uniprot Description

Reversible hydration of carbon dioxide.

Research Articles on CA12

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Product Notes

The CA12 ca12 (Catalog #AAA854952) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CA12 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CA12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:40000. Researchers should empirically determine the suitability of the CA12 ca12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CA12, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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