Western Blot (WB)
(RPH3A Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RPH3A antibody detected the RPH3A protein (arrow).)
Rabbit RPH3A Polyclonal Antibody | anti-RPH3A antibody
RPH3A Antibody (C-term)
Western Blot (WB)
(RPH3A Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RPH3A antibody detected the RPH3A protein (arrow).)
Western Blot (WB)
(RPH3A Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RPH3A antibody detected the RPH3A protein (arrow).)
fundamental to synaptic neurotransmission and cell-cell
communication. RAB3A (MIM 179390) is a small G protein that is
thought to act at late stages of exocytosis, and RPH3A is a RAB3A
effector (Lin et al., 2007 [PubMed 17149709]).
Smith, R., et al. J. Neurochem. 103(1):115-123(2007)
Lin, C.C., et al. J. Cell. Physiol. 211(2):316-326(2007)
Dalfo, E., et al. Neurobiol. Dis. 16(1):92-97(2004)
Rastaldi, M.P., et al. Am. J. Pathol. 163(3):889-899(2003)
NCBI and Uniprot Product Information
NCBI Description
Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).[supplied by OMIM, Jul 2008]
Uniprot Description
rabphilin 3A: Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 12q24.13
Cellular Component: Golgi apparatus; synaptic vesicle; neuron projection; protein complex; extrinsic to membrane; synaptic vesicle membrane; synapse; cell junction; cytosol; secretory granule
Molecular Function: selenium binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; zinc ion binding; calcium-dependent phospholipid binding; transporter activity; protein complex binding; calcium ion binding; phosphate binding; Rab GTPase binding
Biological Process: intracellular protein transport
Research Articles on RPH3A
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Product Notes
The RPH3A rph3a (Catalog #AAA9203168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 658-686. The RPH3A Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's RPH3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RPH3A rph3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPH3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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