Human, Mouse VAV2 ELISA Kit | VAV2 elisa kit

VAV2 Colorimetric Cell-Based ELISA Kit

Gene Names

VAV2; VAV-2

Reactivity

Human, Mouse

Synonyms

VAV2; VAV2 Colorimetric Cell-Based ELISA Kit; Vav-2 protein; Guanine nucleotide exchange factor VAV2; VAV-2; VAV2 elisa kit

Ordering
Cat. Num. AAA9500618 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Human, Mouse

Form/Format

One 96-Well Plate

Sequence Length

878

Samples

Researchers plate their cell line of choice

Assay Type

Non-Phospho Cell-Based ELISA

Sensitivity

>=5000 cells/well

Detection Method

Colorimetric 450 nm

Preparation and Storage

Store at 4 degree C.

Product Categories/Family for VAV2 elisa kit

Cell Based ELISA Kit

NCBI and Uniprot Product Information

NCBI GI #

197304715

NCBI GeneID

7410

NCBI Accession #

NP_001127870.1

NCBI GenBank Nucleotide #

NM_001134398.1

UniProt Accession #

P52735; Q5SYV3; Q5SYV4; Q5SYV5; Q6N012; Q6PIJ9; Q6Q317; A2RUM4; A8MQ12; B6ZDF5

Molecular Weight

101257

NCBI Official Full Name

guanine nucleotide exchange factor VAV2 isoform 1

NCBI Official Synonym Full Names

vav guanine nucleotide exchange factor 2

NCBI Official Symbol

VAV2

NCBI Official Synonym Symbols

VAV-2

NCBI Protein Information

guanine nucleotide exchange factor VAV2

UniProt Protein Name

Guanine nucleotide exchange factor VAV2

Protein Family

Guanine nucleotide exchange factor

UniProt Gene Name

VAV2

UniProt Synonym Gene Names

VAV-2

NCBI Description

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Uniprot Description

VAV2: a proto-oncogenic guanine nucleotide exchange factors (GEF) of the Dbl family. A GEF for the Rho family of GTP binding proteins. Expressed in most tissues.

Protein type: GEF; GEF, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 9q34.2

Cellular Component: cytosol; plasma membrane

Molecular Function: epidermal growth factor receptor binding; guanyl-nucleotide exchange factor activity; metal ion binding; phosphotyrosine binding; protein binding; Rho guanyl-nucleotide exchange factor activity

Biological Process: angiogenesis; cell migration; ephrin receptor signaling pathway; Fc-epsilon receptor signaling pathway; Fc-gamma receptor signaling pathway involved in phagocytosis; G-protein coupled receptor signaling pathway; lamellipodium assembly; platelet activation; positive regulation of apoptosis; positive regulation of phosphatidylinositol 3-kinase activity; regulation of blood coagulation; regulation of cell size; regulation of gene expression; regulation of GTPase activity; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; signal transduction; small GTPase mediated signal transduction; vascular endothelial growth factor receptor signaling pathway

Research Articles on VAV2

1. High VAV2 expression is associated with breast cancer.

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Product Notes

The Human, Mouse VAV2 vav2 (Catalog #AAA9500618) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9500618 ELISA Kit recognizes Human, Mouse VAV2. It is sometimes possible for the material contained within the vial of "VAV2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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