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Human, Mouse EPB41 ELISA Kit | EPB41 elisa kit

Phospho-EPB41 (Tyr660/418) Colorimetric Cell-Based ELISA Kit

Gene Names
EPB41; HE; EL1; 4.1R
Reactivity
Human, Mouse
Synonyms
EPB41; Phospho-EPB41 (Tyr660/418) Colorimetric Cell-Based ELISA Kit; 4.1R; 41; band 4.1; E41P; EPB4.1; erythrocyte membrane protein band 4.1; P4.1; protein 4.1; EPB41 elisa kit
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Form/Format
Two 96-Well Plates
Sequence Length
864
Samples
Researchers plate their cell line of choice
Assay Type
Phospho Cell-Based ELISA
Sensitivity
>=5000 cells/well
Reactivity Note
Human: Y660, Mouse: Y654
Detection Method
Colorimetric 450 nm
Preparation and Storage
Store at 4 degree C.
Product Categories/Family for EPB41 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
97017
NCBI Official Full Name
protein 4.1 isoform 1
NCBI Official Synonym Full Names
erythrocyte membrane protein band 4.1
NCBI Official Symbol
EPB41
NCBI Official Synonym Symbols
HE; EL1; 4.1R
NCBI Protein Information
protein 4.1
UniProt Protein Name
Protein 4.1
Protein Family
UniProt Gene Name
EPB41
UniProt Synonym Gene Names
E41P; P4.1

NCBI Description

The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Oct 2009]

Uniprot Description

Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127).

Research Articles on EPB41

Similar Products

Product Notes

The Human, Mouse EPB41 epb41 (Catalog #AAA9501675) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501675 ELISA Kit recognizes Human, Mouse EPB41. It is sometimes possible for the material contained within the vial of "EPB41, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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