Western Blot (WB)
(Host: RabbitTarget Name: ARCN1Sample Tissue: Human HepG2Antibody Dilution: 1.0ug/ml)
Rabbit ARCN1 Polyclonal Antibody | anti-ARCN1 antibody
ARCN1 antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: ARCN1Sample Tissue: Human HepG2Antibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ARCN1Sample Tissue: Human HepG2Antibody Dilution: 1.0ug/ml)
Western Blot (WB)
(WB Suggested Anti-ARCN1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-ARCN1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate)
Target Description: The gene that encodes ARCN1 maps in a region, which includes the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. ARCN1 is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking.This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking.
NCBI and Uniprot Product Information
NCBI Description
This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq, Jul 2008]
Uniprot Description
ARCN1: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: Golgi apparatus; clathrin adaptor complex; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; COPI vesicle coat; cytosol
Biological Process: cerebellar Purkinje cell layer maturation; intracellular protein transport; COPI coating of Golgi vesicle; pigmentation; adult locomotory behavior; retrograde vesicle-mediated transport, Golgi to ER
Research Articles on ARCN1
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Product Notes
The ARCN1 arcn1 (Catalog #AAA3211754) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARCN1 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's ARCN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ARCN1 arcn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GGLQNMELHG MIMLRISDDK YGRIRLHVEN EDKKGVQLQT HPNVDKKLFT. It is sometimes possible for the material contained within the vial of "ARCN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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