Western Blot (WB)
(Western blot analysis of extracts from Jurkat cells and HeLa cells, using SPR1 antibody.)
anti-Human, Mouse SPR1 Antibody | anti-SPR1 antibody
SPR1 Antibody
Gene Names
GPR68; OGR1; AI2A6; GPR12A
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SPR1; SPR1 Antibody; Sphingosylphosphorylcholine receptor; Ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A; OGR1; anti-SPR1 antibody
Reactivity
Human, Mouse
Specificity
SPR1 antibody detects endogenous levels of total SPR1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
365
Applicable Applications for anti-SPR1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:5000
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human SPR1.
Preparation and Storage
Store at-20 degree C for 1 year.
Western Blot (WB)
(Western blot analysis of extracts from Jurkat cells and HeLa cells, using SPR1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from Jurkat cells and HeLa cells, using SPR1 antibody.)
Product Categories/Family for anti-SPR1 antibody
References
An S., FEBS Lett. 375:121-124(1995). Xu Y., Genomics 35:397-402(1996). King M.M., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,077 Da
NCBI Official Full Name
ovarian cancer G-protein coupled receptor 1
NCBI Official Synonym Full Names
G protein-coupled receptor 68
NCBI Official Symbol
GPR68
NCBI Official Synonym Symbols
OGR1; AI2A6; GPR12A
NCBI Protein Information
ovarian cancer G-protein coupled receptor 1
UniProt Protein Name
Ovarian cancer G-protein coupled receptor 1
Protein Family
UniProt Gene Name
GPR68
UniProt Synonym Gene Names
OGR1; OGR-1
NCBI Description
The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
Uniprot Description
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer ().
Research Articles on SPR1
Similar Products
Product Notes
The SPR1 gpr68 (Catalog #AAA854132) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SPR1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SPR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the SPR1 gpr68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPR1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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