Testing Data
(Image: NBS1 staining of paraffin-embedded mouse bone marrow.)
anti-Human, Mouse p95/NBS1 Antibody | anti-p95/NBS1 antibody
p95/NBS1, Affinity Purified Antibody, Rabbit
Testing Data
(Image: NBS1 staining of paraffin-embedded mouse bone marrow.)
Testing Data
(Image: NBS1 staining of paraffin-embedded mouse bone marrow.)
Testing Data
Testing Data
NCBI and Uniprot Product Information
Uniprot Description
NBS1: a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.
Protein type: DNA repair, damage; Cell cycle regulation
Cellular Component: chromosome, telomeric region; PML body; Mre11 complex; nuclear chromosome, telomeric region; nucleolus; replication fork; chromosome; intracellular; nucleus; nuclear inclusion body
Molecular Function: ATP-dependent DNA helicase activity; damaged DNA binding; protein N-terminus binding; transcription factor binding
Biological Process: in utero embryonic development; negative regulation of virion penetration into host cell; mitotic cell cycle checkpoint; regulation of fibroblast proliferation; isotype switching; positive regulation of kinase activity; DNA repair; cell cycle; positive regulation of protein amino acid autophosphorylation; DNA duplex unwinding; cell proliferation; negative regulation of neuron differentiation; meiotic cell cycle; mitotic cell cycle G2/M transition DNA damage checkpoint; double-strand break repair; DNA damage checkpoint; positive regulation of cell proliferation; blastocyst growth; neuromuscular process controlling balance; response to DNA damage stimulus; telomere maintenance
Research Articles on p95/NBS1
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Product Notes
The p95/NBS1 nbn (Catalog #AAA555117) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The p95/NBS1, Affinity Purified Antibody, Rabbit reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's p95/NBS1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the p95/NBS1 nbn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p95/NBS1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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