BCMA:Fc Active Protein

BCMA:Fc, Recombinant, Human (B Cell Maturation Protein, CD269, TNFRSF17)

Cat. Num. AAA635721

• Purity: Highly Purified; >95% (SDS-PAGE)
• Synonyms: BCMA:Fc; Recombinant; Human (B Cell Maturation Protein; CD269; TNFRSF17); BCMA:Fc active protein

• Host: Human, HEK 293 cells
• Specificity: Binds human and mouse BAFF and APRIL.
• Purity/Purification: Highly Purified; >95% (SDS-PAGE)
• Form/Format: Supplied as a lyophilized powder in PBS pH 7.2. Reconstitute with 50ul ddH2O.
• Concentration: ~1mg/ml (after reconstitution) (varies by lot)
• Sequence: The extracellular domain of human BCMA (aa 2-54) is fused at the C-terminus to the Fc portion of human IgG1.

• Biological Activity: Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation.
• Endotoxin: <0.01Eu/ig (LAL)
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months after receipt at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for BCMA:Fc active protein

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappaB and JNK.
Binds human and mouse BAFF and APRIL.

Product Categories/Family for BCMA:Fc active protein

Molecular Biology; MB-CD Markers