Typical Testing Data/Standard Curve (for reference only)
Human Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) ELISA Kit | TNFRSF4 elisa kit
Human Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to TNFRSF4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to TNFRSF4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain TNFRSF4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of TNFRSF4 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Uniprot Description
TNFRSF4: Receptor for TNFSF4/OX40L/GP34.
Protein type: Apoptosis; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: cell surface; integral component of plasma membrane; plasma membrane
Molecular Function: tumor necrosis factor-activated receptor activity; viral receptor activity
Biological Process: entry of virus into host cell; immune response; inflammatory response; multicellular organism development; negative regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; positive regulation of B cell proliferation; positive regulation of immunoglobulin secretion; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; T cell proliferation; tumor necrosis factor-mediated signaling pathway
Disease: Immunodeficiency 16
Research Articles on TNFRSF4
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Product Notes
The Human TNFRSF4 tnfrsf4 (Catalog #AAA456926) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA456926 ELISA Kit recognizes Human TNFRSF4. It is sometimes possible for the material contained within the vial of "Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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