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Typical Testing Data/Standard Curve (for reference only)

Human TIMP4 ELISA Kit | TIMP4 elisa kit

Human TIMP4 ELISA Kit

Reactivity
Human
Applications
ELISA
Synonyms
TIMP4; Human TIMP4 ELISA Kit; Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
224
Applicable Applications for TIMP4 elisa kit
Sandwich ELISA (SE)
Samples
Cell Culture Supernatants, Serum, Plasma
Assay Type
Sandwich
Detection Range
78 pg/ml - 5000 pg/ml
Sensitivity
10 pg/ml
Detection Method
Colorimetric
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for TIMP4 elisa kit
Sandwich ELISA for quantitative detection of Human TIMP4 concentrations.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,503 Da
NCBI Official Full Name
metalloproteinase inhibitor 4
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 4
NCBI Official Symbol
TIMP4
NCBI Protein Information
metalloproteinase inhibitor 4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4
UniProt Protein Name
Metalloproteinase inhibitor 4
UniProt Gene Name
TIMP4
UniProt Synonym Gene Names
TIMP-4
UniProt Entry Name
TIMP4_HUMAN

NCBI Description

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008]

Uniprot Description

TIMP4: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. Belongs to the protease inhibitor I35 (TIMP) family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: proteinaceous extracellular matrix; extracellular space; sarcomere

Molecular Function: metalloendopeptidase inhibitor activity; protease binding; metal ion binding

Biological Process: response to drug; response to peptide hormone stimulus; negative regulation of metalloenzyme activity; ovulation cycle; central nervous system development; response to cytokine stimulus; response to hormone stimulus; response to lipopolysaccharide; negative regulation of membrane protein ectodomain proteolysis

Research Articles on TIMP4

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Product Notes

The Human TIMP4 timp4 (Catalog #AAA825008) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA825008 ELISA Kit recognizes Human TIMP4. AAA Biotech's TIMP4 can be used in a range of immunoassay formats including, but not limited to, Sandwich ELISA (SE). Researchers should empirically determine the suitability of the TIMP4 timp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIMP4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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