Human Thymosin beta4 ELISA Kit | TMSB4X elisa kit

Human Thymosin beta4 ELISA Kit

Cat. Num. AAA2605327

• Gene Names: TMSB4X; FX; TB4X; PTMB4; TMSB4
• Reactivity: Human
• Synonyms: Thymosin beta4; Human Thymosin beta4 ELISA Kit; TMSB4X elisa kit

• Reactivity: Human
• Specificity: No cross-reaction with other factors.
• Sequence Length: 44

• Samples: Human serum, plasma or cell culture supernatant
• Assay Type: Quantitative Sandwich
• Detection Range: 100 ng/ml-1.56 ng/ml
• Sensitivity: Up to 0.5 ng/ml
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for TMSB4X elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human Tbeta4 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 11056061
• NCBI GeneID: 7114
• NCBI Accession #: NP_066932.1
• NCBI GenBank Nucleotide #: NM_021109.3
• Molecular Weight: 5,053 Da
• NCBI Official Full Name: thymosin beta-4
• NCBI Official Synonym Full Names: thymosin beta 4, X-linked
• NCBI Official Symbol: TMSB4X
• NCBI Official Synonym Symbols: FX; TB4X; PTMB4; TMSB4
• NCBI Protein Information: thymosin beta-4
• UniProt Protein Name: Thymosin beta-4
• Protein Family: Thymosin
• UniProt Gene Name: TMSB4X
• UniProt Synonym Gene Names: TB4X; THYB4; TMSB4; T beta-4
• UniProt Entry Name: TYB4_HUMAN

NCBI Description

This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008]

Uniprot Description

TMSB4X: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq21.3-q22

Cellular Component: cytoskeleton; extracellular region

Molecular Function: actin monomer binding; protein binding

Biological Process: actin filament organization; blood coagulation; platelet activation; platelet degranulation