Human SSTR3 ELISA Kit | SSTR3 elisa kit

Human SSTR3 (Somatostatin Receptor 3) ELISA Kit

Cat. Num. AAA2515726

• Gene Names: SSTR3; SS3R; SS3-R; SS-3-R; SSR-28
• Reactivity: Human
• Synonyms: SSTR3; Human SSTR3 (Somatostatin Receptor 3) ELISA Kit; SSTR3 elisa kit

• Reactivity: Human
• Specificity: This kit recognizes natural and recombinantHumanSSTR3. No significant cross-reactivity or interference between HumanSSTR3 and analogues was observed.
• Sequence Length: 418

• Samples: Serum, Plasma, Biological Fluids
• Assay Type: Sandwich
• Detection Range: 62.5-4000pg/mL
• Sensitivity: Min: 37.5pg/mL; Max: 4000pg/mL
• Preparation and Storage: Store at 4 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for SSTR3 elisa kit

Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanSSTR3concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to SSTR3. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for SSTR3and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain SSTR3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of SSTR3.You can calculate the concentration of SSTR3in the samples by comparing the OD of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 522838250
• NCBI GeneID: 6753
• NCBI Accession #: NP_001265616.1
• NCBI GenBank Nucleotide #: NM_001278687.2
• Molecular Weight: 45,847 Da
• NCBI Official Full Name: somatostatin receptor type 3
• NCBI Official Synonym Full Names: somatostatin receptor 3
• NCBI Official Symbol: SSTR3
• NCBI Official Synonym Symbols: SS3R; SS3-R; SS-3-R; SSR-28
• NCBI Protein Information: somatostatin receptor type 3
• UniProt Protein Name: Somatostatin receptor type 3
• Protein Family: Somatostatin receptor
• UniProt Gene Name: SSTR3
• UniProt Synonym Gene Names: SS-3-R; SS3-R; SS3R
• UniProt Entry Name: SSR3_HUMAN

NCBI Description

This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

SSTR3: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: neuron projection; nonmotile primary cilium; integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: neuropeptide binding; protein binding; somatostatin receptor activity

Biological Process: response to starvation; synaptic transmission; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; induction of apoptosis by hormones; neuropeptide signaling pathway; organelle organization and biogenesis; forebrain development; cerebellum development; spermatogenesis; regulation of insulin secretion