Human Septin 5 (SEPT5) ELISA Kit | SEPT5 elisa kit

Human Septin 5 (SEPT5) ELISA Kit

Cat. Num. AAA451319

• Gene Names: SEPT5; H5; CDCREL; PNUTL1; CDCREL1; CDCREL-1; HCDCREL-1
• Reactivity: Human
• Synonyms: Septin 5 (SEPT5); Human Septin 5 (SEPT5) ELISA Kit; CDCREL; CDCREL-1; CDCREL1; H5; PNUTL1; Peanut-Like 1; Cell division control-related protein 1; SEPT5 elisa kit

• Reactivity: Human
• Sequence Length: 346

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.126ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 58331274
• NCBI GeneID: 5413
• NCBI Accession #: NP_001009939.1
• NCBI GenBank Nucleotide #: NM_001009939.2
• UniProt Accession #: Q99719; O15251; Q96MY5
• Molecular Weight: 39,332 Da
• NCBI Official Full Name: septin-5 isoform 2
• NCBI Official Synonym Full Names: septin 5
• NCBI Official Symbol: SEPT5
• NCBI Official Synonym Symbols: H5; CDCREL; PNUTL1; CDCREL1; CDCREL-1; HCDCREL-1
• NCBI Protein Information: septin-5
• UniProt Protein Name: Septin-5
• UniProt Gene Name: SEPT5
• UniProt Synonym Gene Names: PNUTL1; CDCrel-1

NCBI Description

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]

Uniprot Description

Filament-forming cytoskeletal GTPase (). May play a role in cytokinesis (Potential). May play a role in platelet secretion ().