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Human ring finger and FYVE-like domain containing 1 ELISA Kit | RFFL elisa kit

Human E3 ubiquitin-protein ligase rififylin, RFFL ELISA Kit

Gene Names
RFFL; CARP2; FRING; CARP-2; RNF189; RNF34L; RIFIFYLIN
Reactivity
Human
Synonyms
ring finger and FYVE-like domain containing 1; Human E3 ubiquitin-protein ligase rififylin; RFFL ELISA Kit; RFFL elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Preparation and Storage
Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,514 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase rififylin
NCBI Official Synonym Full Names
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
NCBI Official Symbol
RFFL
NCBI Official Synonym Symbols
CARP2; FRING; CARP-2; RNF189; RNF34L; RIFIFYLIN
NCBI Protein Information
E3 ubiquitin-protein ligase rififylin; RING finger protein 189; caspase regulator CARP2; FYVE-RING finger protein SAKURA; ring finger and FYVE-like domain containing 1; caspases-8 and -10-associated RING finger protein 2; RING finger and FYVE-like domain-containing protein 1
UniProt Protein Name
E3 ubiquitin-protein ligase rififylin
UniProt Gene Name
RFFL
UniProt Synonym Gene Names
RNF189; RNF34L; CARP-2; Fring
UniProt Entry Name
RFFL_HUMAN

Uniprot Description

RFFL: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Ligase; Ubiquitin conjugating system; EC 6.3.2.-; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: Golgi membrane; membrane; recycling endosome membrane; lysosome; cytoplasm; cytoplasmic membrane-bound vesicle; plasma membrane; endosome membrane; cytosol

Molecular Function: protein binding; protease binding; zinc ion binding; p53 binding; ubiquitin protein ligase binding; protein kinase binding; ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; intracellular protein transport; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of TOR signaling pathway

Research Articles on RFFL

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Product Notes

The Human RFFL rffl (Catalog #AAA2602871) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2602871 ELISA Kit recognizes Human RFFL. It is sometimes possible for the material contained within the vial of "ring finger and FYVE-like domain containing 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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