Human RGC32/Response Gene To Complement 32 Protein ELISA Kit | RGC32 elisa kit

Human RGC32/Response Gene To Complement 32 Protein ELISA Kit

Cat. Num. AAA2890938

• Gene Names: RGCC; RGC32; RGC-32; C13orf15; bA157L14.2
• Reactivity: Human
• Synonyms: RGC32/Response Gene To Complement 32 Protein; Human RGC32/Response Gene To Complement 32 Protein ELISA Kit; Response gene to complement 32 protein; C13orf15; RGC32 elisa kit

• Reactivity: Human
• Specificity: Natural and recombinant Human Response gene to complement 32 protein
• Sequence Length: 137

• Assay Type: Sandwich
• Detection Range: 78-5000pg/mL
• Sensitivity: 39.8pg/mL
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 132626811
• NCBI GeneID: 28984
• NCBI Accession #: NP_054778.2
• NCBI GenBank Nucleotide #: NM_014059.3
• UniProt Accession #: Q9H4X1
• NCBI Official Full Name: regulator of cell cycle RGCC
• NCBI Official Synonym Full Names: regulator of cell cycle
• NCBI Official Symbol: RGCC
• NCBI Official Synonym Symbols: RGC32; RGC-32; C13orf15; bA157L14.2
• NCBI Protein Information: regulator of cell cycle RGCC
• UniProt Protein Name: Regulator of cell cycle RGCC
• UniProt Gene Name: RGCC
• UniProt Synonym Gene Names: C13orf15; RGC32; RGC-32

NCBI Description

This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]

Uniprot Description

Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.