Typical Testing Data/Standard Curve (for reference only)

Human Procollagen I C-Terminal Propeptide (PICP) ELISA Kit | PICP elisa kit

Human Procollagen I C-Terminal Propeptide (PICP) ELISA KIT

Gene Names

PCOLCE; PCPE; PCPE1; PCPE-1

Reactivity

Human

Synonyms

Procollagen I C-Terminal Propeptide (PICP); Human Procollagen I C-Terminal Propeptide (PICP) ELISA KIT; PICP elisa kit

Ordering
Cat. Num. AAA260379 For Research Use Only!

Reactivity

Human

Sequence Length

449

Samples

Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant PICP concentration

Assay Type

Sandwich

Detection Range

50 ng/ml-0.78 ng/ml

Sensitivity

0.08ng/ml.

Intra-assay Precision

<= 8%

Inter-assay Precision

<= 12%

Preparation and Storage

Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for PICP elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human PICP monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

NCBI GI #

157653329

NCBI GeneID

5118

NCBI Accession #

NP_002584.2

NCBI GenBank Nucleotide #

NM_002593.3

Molecular Weight

47,972 Da

NCBI Official Full Name

procollagen C-endopeptidase enhancer 1

NCBI Official Synonym Full Names

procollagen C-endopeptidase enhancer

NCBI Official Symbol

PCOLCE

NCBI Official Synonym Symbols

PCPE; PCPE1; PCPE-1

NCBI Protein Information

procollagen C-endopeptidase enhancer 1; procollagen C-proteinase enhancer 1; procollagen COOH-terminal proteinase enhancer 1; type 1 procollagen C-proteinase enhancer protein; type I procollagen COOH-terminal proteinase enhancer; procollagen, type 1, COOH-terminal proteinase enhancer

UniProt Protein Name

Procollagen C-endopeptidase enhancer 1

UniProt Gene Name

PCOLCE

UniProt Synonym Gene Names

PCPE1; PCPE-1; Procollagen C-proteinase enhancer 1

UniProt Entry Name

PCOC1_HUMAN

NCBI Description

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008]

Uniprot Description

PCOLCE: Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.

Protein type: Extracellular matrix; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: extracellular matrix; extracellular space

Molecular Function: heparin binding; collagen binding; protein binding; protease activator activity

Biological Process: multicellular organismal development; proteolysis

Research Articles on PICP

1. The analysis of the PCPE-1 interaction network based on Gene Ontology terms suggests that, besides its role in collagen deposition, PCPE-1 might be involved in tumour growth, neurodegenerative diseases and angiogenesis.

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Product Notes

The Human PICP pcolce (Catalog #AAA260379) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA260379 ELISA Kit recognizes Human PICP. It is sometimes possible for the material contained within the vial of "Procollagen I C-Terminal Propeptide (PICP), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Human Procollagen I C-Terminal Propeptide (PICP) ELISA Kit | PICP elisa kit