Human Polypeptide N-acetylgalactosaminyltransferase 13, GALNT13 ELISA Kit | GALNT13 elisa kit
Human Polypeptide N-acetylgalactosaminyltransferase 13, GALNT13 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]
Uniprot Description
GALNT13: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.4.1.41; Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 2q23.3-q24.1
Cellular Component: Golgi membrane; integral component of membrane
Molecular Function: carbohydrate binding; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity
Biological Process: O-glycan processing; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine
Research Articles on GALNT13
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Product Notes
The Human GALNT13 galnt13 (Catalog #AAA1606774) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1606774 ELISA Kit recognizes Human GALNT13. It is sometimes possible for the material contained within the vial of "Polypeptide N-acetylgalactosaminyltransferase 13, GALNT13, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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