Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Peroxiredoxin 4 (PRDX4) Standard Curve.)
Human Peroxiredoxin 4 (PRDX4) ELISA Kit | PRDX4 elisa kit
Human Peroxiredoxin 4 (PRDX4) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Peroxiredoxin 4 (PRDX4) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Peroxiredoxin 4 (PRDX4) Standard Curve.)
Background: Peroxiredoxin-4 is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.Sequence analysis predicted that the 271-amino acid protein, 70% identical to a yeast thiol-specific antioxidant, contains a signal peptide and 2 peroxide catalysis cysteine motifs conserved in all human peroxiredoxins. Functional analysis showed that PRDX4 protects glutamine synthetase (GLUL) from inactivation.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]
Uniprot Description
PRDX4: Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the AhpC/TSA family.
Protein type: Secreted; Mitochondrial; Oxidoreductase; EC 1.11.1.15; Secreted, signal peptide
Chromosomal Location of Human Ortholog: Xp22.11
Cellular Component: extracellular space; smooth endoplasmic reticulum; mitochondrion; nucleus; cytosol
Molecular Function: protein binding; protein homodimerization activity; thioredoxin peroxidase activity
Biological Process: extracellular matrix organization and biogenesis; protein maturation via protein folding; 4-hydroxyproline metabolic process; cell redox homeostasis; male gonad development; spermatogenesis; I-kappaB phosphorylation
Research Articles on PRDX4
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Product Notes
The Human PRDX4 prdx4 (Catalog #AAA9714845) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714845 ELISA Kit recognizes Human PRDX4. It is sometimes possible for the material contained within the vial of "Peroxiredoxin 4 (PRDX4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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