Human Peptidase D (PEPD) ELISA Kit | PEPD elisa kit

Human Peptidase D (PEPD) ELISA Kit

Cat. Num. AAA451202

• Gene Names: PEPD; PROLIDASE
• Reactivity: Human
• Synonyms: Peptidase D (PEPD); Human Peptidase D (PEPD) ELISA Kit; PRD Xaa-Pro Dipeptidase Prolidase Imidodipeptidase Proline dipeptidase; PEPD elisa kit

• Reactivity: Human
• Sequence Length: 493

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 1.56-100ng/mL
• Sensitivity: 0.63ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 149589008
• NCBI GeneID: 5184
• NCBI Accession #: NP_000276.2
• NCBI GenBank Nucleotide #: NM_000285.3
• UniProt Accession #: P12955; Q8TBN9; Q9BT75; A8K3Z1; A8K416; A8K696; A8MX47; B4DDB7; B4DGJ1; E9PCE8
• Molecular Weight: 47,261 Da
• NCBI Official Full Name: xaa-Pro dipeptidase isoform 1
• NCBI Official Synonym Full Names: peptidase D
• NCBI Official Symbol: PEPD
• NCBI Official Synonym Symbols: PROLIDASE
• NCBI Protein Information: xaa-Pro dipeptidase
• UniProt Protein Name: Xaa-Pro dipeptidase
• Protein Family: Dipeptidase
• UniProt Gene Name: PEPD
• UniProt Synonym Gene Names: PRD; X-Pro dipeptidase; Prolidase

NCBI Description

This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Uniprot Description

Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen.