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Interleukin-7 Receptor Subunit alpha Recombinant Protein | Il7r recombinant protein
Recombinant Mouse Interleukin-7 Receptor Subunit alpha Protein
Gene Names
Il7r; CD127; IL-7Ralpha
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Interleukin-7 Receptor Subunit alpha; Recombinant Mouse Interleukin-7 Receptor Subunit alpha Protein; Interleukin-7 receptor subunit alpha; Il7r; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127; Il7r recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
Sequence Length
459
Species
Mouse
Endotoxin
<1.0 EU per mug as determined by LAL test.
Fragment
Met 1-Asp 239
Fusion Tag
C-Fc
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
SDS-Page
SDS-Page
Related Product Information for Il7r recombinant protein
Protein Construction: Recombinant Mouse Interleukin-7 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu21-Asp239 is expressed with a Fc tag at the C-terminus.
Background: Interleukin 7 Receptor alpha (IL-7Ralpha), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Ralpha is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Ralpha is important for the generation of appropriate immune responses.
Background: Interleukin 7 Receptor alpha (IL-7Ralpha), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Ralpha is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Ralpha is important for the generation of appropriate immune responses.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 52.1kDa
Actual Protein Molecular Mass: 61-75kDa
Actual Protein Molecular Mass: 61-75kDa
NCBI Official Full Name
interleukin-7 receptor subunit alpha isoform 1
NCBI Official Synonym Full Names
interleukin 7 receptor
NCBI Official Symbol
Il7r
NCBI Official Synonym Symbols
CD127; IL-7Ralpha
NCBI Protein Information
interleukin-7 receptor subunit alpha
UniProt Protein Name
Interleukin-7 receptor subunit alpha
Protein Family
UniProt Gene Name
Il7r
UniProt Synonym Gene Names
IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA
NCBI Description
Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008]
Uniprot Description
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Research Articles on Il7r
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Product Notes
The Il7r il7r (Catalog #AAA2556797) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Interleukin-7 Receptor Subunit alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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