Human Microsomal Triglyceride Transfer Protein (MTTP) ELISA Kit | MTTP elisa kit

Human Microsomal Triglyceride Transfer Protein (MTTP) ELISA Kit

Cat. Num. AAA167168

• Gene Names: MTTP; ABL; MTP
• Reactivity: Human
• Synonyms: Microsomal Triglyceride Transfer Protein (MTTP); Human Microsomal Triglyceride Transfer Protein (MTTP) ELISA Kit; MTTP elisa kit

• Reactivity: Human
• Sequence Length: 20

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 5ng/L - 2000ng/L
• Sensitivity: 2.43ng/L
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for MTTP elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Microsomal Triglyceride Transfer Protein (also known as MTTP) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human MTTP antibody. MTTP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human MTTP Antibody is added and binds to MTTP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated MTTP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human MTTP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 4261846
• NCBI GeneID: 4547
• Molecular Weight: 16,865 Da
• NCBI Official Full Name: microsomal triglyceride transfer protein, partial
• NCBI Official Synonym Full Names: microsomal triglyceride transfer protein
• NCBI Official Symbol: MTTP
• NCBI Official Synonym Symbols: ABL; MTP
• NCBI Protein Information: microsomal triglyceride transfer protein large subunit
• UniProt Protein Name: Microsomal triglyceride transfer protein large subunit
• Protein Family: Microsomal triglyceride transfer protein
• UniProt Gene Name: MTTP
• UniProt Synonym Gene Names: MTP

NCBI Description

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]

Uniprot Description

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406). Required for the secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612, PubMed:8939939, PubMed:26224785).