Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Meningioma (disrupted in balanced translocation) 1 (MN1) Standard Curve.)
Human Meningioma (Disrupted In Balanced Translocation) 1 (MN1) ELISA Kit | MN1 elisa kit
Human Meningioma (Disrupted In Balanced Translocation) 1 (MN1) ELISA Kit
Gene Names
MN1; MGCR; MGCR1; MGCR1-PEN; dJ353E16.2
Reactivity
Human
Synonyms
Meningioma (Disrupted In Balanced Translocation) 1 (MN1); Human Meningioma (Disrupted In Balanced Translocation) 1 (MN1) ELISA Kit; MN1; CTA-437G10__B.1; MGCR; MGCR1; MGCR1-PEN; dJ353E16.2; bK437G10B.1 (meningioma (disrupted in balanced translocation) 1); meningioma 1; meningioma (translocation balanced); meningioma chromosome region 1; MN1 elisa kit
Reactivity
Human
Specificity
Human Meningioma (disrupted in balanced translocation) 1 (MN1) ELISA Kit has high sensitivity and excellent specificity for detection of Human MN1. No significant cross-reactivity or interference between Human MN1 and analogues was observed.
Sequence Length
1320
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Meningioma (disrupted in balanced translocation) 1 (MN1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Meningioma (disrupted in balanced translocation) 1 (MN1) Standard Curve.)
Related Product Information for MN1 elisa kit
Description: This Human Meningioma (disrupted in balanced translocation) 1 (MN1) ELISA Kit employs a two-site sandwich ELISA to quantitate MN1 in samples. An antibody specific for MN1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MN1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MN1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MN1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.
Background: Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
transcriptional activator MN1
NCBI Official Synonym Full Names
MN1 proto-oncogene, transcriptional regulator
NCBI Official Symbol
MN1
NCBI Official Synonym Symbols
MGCR; MGCR1; MGCR1-PEN; dJ353E16.2
NCBI Protein Information
transcriptional activator MN1
UniProt Protein Name
Probable tumor suppressor protein MN1
Protein Family
UniProt Gene Name
MN1
UniProt Entry Name
MN1_HUMAN
NCBI Description
Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
MN1: May play a role in tumor suppression. A chromosomal aberration involving MN1 may be a cause of acute myeloid leukemia (AML). Translocation t(12;22)(p13;q11) with TEL. Defects in MN1 involved in the development of meningiomas, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord. Meningiomas are believed to be the most common primary tumors of the central nervous system in man.
Protein type: Transcription, coactivator/corepressor; Tumor suppressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 22q12.1
Biological Process: intramembranous ossification
Disease: Meningioma, Familial, Susceptibility To
Research Articles on MN1
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Product Notes
The Human MN1 mn1 (Catalog #AAA9715245) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715245 ELISA Kit recognizes Human MN1. It is sometimes possible for the material contained within the vial of "Meningioma (Disrupted In Balanced Translocation) 1 (MN1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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