Human MACF1/Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 ELISA Kit | MACF1 elisa kit
Human MACF1/Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]
Uniprot Description
ACF7: a nuclear WD40-repeat protein. An F-actin-binding protein which may play a role in cross- linking actin to other cytoskeletal proteins. Also binds to microtubules. WD40 proteins are known to function as adaptors in pre-mrna processing and cytoskeleton assembly.
Protein type: Motility/polarity/chemotaxis; Actin-binding; Cytoskeletal
Chromosomal Location of Human Ortholog: 1p32-p31
Cellular Component: Golgi apparatus; microtubule; cytoskeleton; cytoplasm; plasma membrane; actin cytoskeleton
Molecular Function: actin filament binding; protein binding; microtubule binding; ATPase activity; calcium ion binding; actin binding
Biological Process: regulation of microtubule-based process; Wnt receptor signaling pathway; wound healing; mesoderm formation; metabolic process; positive regulation of axon extension; regulation of focal adhesion formation; Golgi to plasma membrane protein transport; establishment and/or maintenance of cell polarity; posttranslational protein targeting to membrane; cell cycle arrest; positive regulation of Wnt receptor signaling pathway
Research Articles on MACF1
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Product Notes
The Human MACF1 macf1 (Catalog #AAA2904598) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2904598 ELISA Kit recognizes Human MACF1. It is sometimes possible for the material contained within the vial of "MACF1/Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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