Human IMMP2L/Mitochondrial Inner Membrane Protease Subunit 2 ELISA Kit | IMMP2L elisa kit
Human IMMP2L/Mitochondrial Inner Membrane Protease Subunit 2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
IMMP2L: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. Defects in IMMP2L may be a cause of Gilles de la Tourette syndrome (GTS). GTS is a neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Belongs to the peptidase S26 family. IMP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.21.-; Membrane protein, integral; Mitochondrial; Protease
Chromosomal Location of Human Ortholog: 7q31
Molecular Function: peptidase activity; serine-type endopeptidase activity
Biological Process: mitochondrial protein processing; mitochondrial respiratory chain complex assembly; signal peptide processing
Research Articles on IMMP2L
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Product Notes
The Human IMMP2L immp2l (Catalog #AAA2890954) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2890954 ELISA Kit recognizes Human IMMP2L. It is sometimes possible for the material contained within the vial of "IMMP2L/Mitochondrial Inner Membrane Protease Subunit 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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