Human Glutamate Decarboxylase 2, Acid (GAD2) ELISA Kit | GAD2 elisa kit

Human Glutamate Decarboxylase 2, Acid (GAD2) ELISA Kit

Cat. Num. AAA455794

• Gene Names: GAD2; GAD65
• Reactivity: Human
• Synonyms: Glutamate Decarboxylase 2; Acid (GAD2); Human Glutamate Decarboxylase 2; Acid (GAD2) ELISA Kit; GAD65 Pancreatic Islets And Brain; 65kDa 65 kDa glutamic acid decarboxylase Glutamate decarboxylase 65 kDa isoform; GAD2 elisa kit

• Reactivity: Human
• Sequence Length: 585

• Samples: Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.781-50ng/mL
• Sensitivity: 0.23ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 4503875
• NCBI GeneID: 2572
• NCBI Accession #: NP_000809.1
• NCBI GenBank Nucleotide #: NM_000818.2
• UniProt Accession #: Q05329; Q9UD87
• Molecular Weight: 65,411 Da
• NCBI Official Full Name: glutamate decarboxylase 2
• NCBI Official Synonym Full Names: glutamate decarboxylase 2
• NCBI Official Symbol: GAD2
• NCBI Official Synonym Symbols: GAD65
• NCBI Protein Information: glutamate decarboxylase 2
• UniProt Protein Name: Glutamate decarboxylase 2
• Protein Family: Glutamate decarboxylase
• UniProt Gene Name: GAD2
• UniProt Synonym Gene Names: GAD65; GAD-65

NCBI Description

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

Uniprot Description

Catalyzes the production of GABA.