Human Glutamate-Cysteine Ligase Modifier Subunit ELISA Kit | GCLM elisa kit

Human Glutamate-Cysteine Ligase Modifier Subunit ELISA Kit

Cat. Num. AAA3802019

• Gene Names: GCLM; GLCLR
• Reactivity: Human
• Synonyms: Glutamate-Cysteine Ligase Modifier Subunit; Human Glutamate-Cysteine Ligase Modifier Subunit ELISA Kit; GCLM elisa kit

• Reactivity: Human
• Sequence Length: 19

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 12.5 U/L-200 U/L
• Sensitivity: 1 U/L

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for GCLM elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofGLUTAMATE--CYSTEINE LIGASE MODIFIER SUBUNITin the sample, This GLUTAMATE--CYSTEINE LIGASE MODIFIER SUBUNITELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusGLUTAMATE--CYSTEINE LIGASE MODIFIER SUBUNITconcentration. The concentration ofGLUTAMATE--CYSTEINE LIGASE MODIFIER SUBUNITin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 39598916
• NCBI GeneID: 2730
• NCBI Official Full Name: glutamate-cysteine ligase modifier subunit, partial
• NCBI Official Synonym Full Names: glutamate-cysteine ligase modifier subunit
• NCBI Official Symbol: GCLM
• NCBI Official Synonym Symbols: GLCLR
• NCBI Protein Information: glutamate--cysteine ligase regulatory subunit
• Protein Family: Glutamate--cysteine ligase regulatory

NCBI Description

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]