Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) Standard Curve.)
Human A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 (ADAMTS7) ELISA Kit | ADAMTS7 elisa kit
Human A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 (ADAMTS7) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) Standard Curve.)
Background: ADAMTS7 is a member of the ADAM protein family. The gene is expressed in human brain, heart, lung, liver, pancreas, kidney, skeletal muscle, and placenta. The murine protein is expressed at low levels throughout mouse development. The predicted 997-amino acid ADAMTS7 protein has a domain structure characteristic of ADAMTSs. The mature ADAMTS7 protein has 2 potential N-linked glycosylation sites. Northern blot analysis detected a 5-kb ADAMTS7 transcript in all human tissues examined, namely brain, heart, lung, liver, pancreas, kidney, skeletal muscle, and placenta; skeletal muscle expressed an additional 7-kb transcript. Mouse Adamts7 was expressed at low levels throughout mouse development.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]
Uniprot Description
ADAMTS7: Metalloprotease that may play a role in the degradation of COMP.
Protein type: Cell surface; Secreted, signal peptide; EC 3.4.24.-; Protease; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 15q24.2
Cellular Component: proteinaceous extracellular matrix; cell surface; endoplasmic reticulum lumen
Molecular Function: protein binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; proteolysis involved in cellular protein catabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification
Research Articles on ADAMTS7
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Product Notes
The Human ADAMTS7 adamts7 (Catalog #AAA9714588) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714588 ELISA Kit recognizes Human ADAMTS7. It is sometimes possible for the material contained within the vial of "A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 (ADAMTS7), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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