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SDS-Page

Tumor-associated Calcium Signal Transducer 2/TROP-2 Active Protein | TROP-2 active protein

Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-6His)

Purity
>95% as determined by reducing SDS-PAGE
Synonyms
Tumor-associated Calcium Signal Transducer 2/TROP-2; Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-6His); Tumor-associated calcium signal transducer 2; Membrane component chromosome 1 surfacemarker 1; Cell surface glycoprotein Trop-2; TACSTD2; TROP2; TROP-2 active protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2um filtered solution of PBS, pH7.4.
Sequence
His27-Arg272
Species
Rhesus Macaque
Tag
C-6His
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding His27-Arg272 is expressed with a 6His tag at the C-terminus.
Activity
Immobilized Rhesus Macaque TROP-2-His at 2ug/ml (100ul/well) can bind Anti-Human TROP-2 mAb.The ED50 of Anti-Human TROP-2 mAb is 4.7ng/ml.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.

SDS-Page

SDS-Page

Activity

Activity
Related Product Information for TROP-2 active protein
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

NCBI and Uniprot Product Information

Molecular Weight
Mol. Mass: 28.7kDa
AP Mol. Mass: 38-45kDa

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Product Notes

The TROP-2 (Catalog #AAA2569417) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: His27-Arg2 72. It is sometimes possible for the material contained within the vial of "Tumor-associated Calcium Signal Transducer 2/TROP-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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