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Carnosine Dipeptidase 1 Active Protein | CNDP1 active protein
Recombinant Human Carnosine Dipeptidase 1 Protein
Gene Names
CNDP1; CN1; CPGL2; HsT2308
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Carnosine Dipeptidase 1; Recombinant Human Carnosine Dipeptidase 1 Protein; Beta-Ala-His Dipeptidase; CNDP Dipeptidase 1; Glutamate Carboxypeptidase-Like Protein 2; Serum Carnosinase; CNDP1; CN1; CPGL2; CNDP1 active protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Sequence Length
507
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fragment
Pro28-His507
Fusion Tag
C-6His
Activity
Measured by its ability to cleave carnosine (beta-Ala-L-His) in a two-step assay. The specific activity is > 250 pmoles/min/mug.
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Please minimize freeze-thaw cycles.
SDS-Page
SDS-Page
Related Product Information for CNDP1 active protein
Protein Construction: Recombinant Human Carnosine Dipeptidase 1 is produced by our Mammalian expression system and the target gene encoding Pro28-His507 is expressed with a 6His tag at the C-terminus.
Background: Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain, serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1,10-o-phenantrolin. In addition, CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine), anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.
Background: Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain, serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1,10-o-phenantrolin. In addition, CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine), anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 54.9kDa
Actual Protein Molecular Mass: 68kDa
Actual Protein Molecular Mass: 68kDa
NCBI Official Full Name
beta-Ala-His dipeptidase
NCBI Official Synonym Full Names
carnosine dipeptidase 1
NCBI Official Symbol
CNDP1
NCBI Official Synonym Symbols
CN1; CPGL2; HsT2308
NCBI Protein Information
beta-Ala-His dipeptidase
UniProt Protein Name
Beta-Ala-His dipeptidase
Protein Family
UniProt Gene Name
CNDP1
UniProt Synonym Gene Names
CN1; CPGL2
NCBI Description
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]
Research Articles on CNDP1
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Product Notes
The CNDP1 cndp1 (Catalog #AAA2556744) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Carnosine Dipeptidase 1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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