TXNDC11 blocking peptide

TXNDC11 Immunizing Peptide

Cat. Num. AAA427703

• Gene Names: TXNDC11; EFP1
• Reactivity: Human
• Synonyms: TXNDC11; TXNDC11 Immunizing Peptide; thioredoxin domain containing 11; EFP1; EF-hand binding protein 1; EF-hand-binding protein 1; thioredoxin domain-containing protein 11; TXNDC11 (aa113-126); TXNDC11 blocking peptide

• Reactivity: Human
• Form/Format: 100ug of dried peptide
• Sequence: C-QLDYAEYVRRDSE
• Sequence Length: 958

• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 54633317
• NCBI GeneID: 51061
• NCBI Accession #: NP_056998.4
• NCBI GenBank Nucleotide #: NM_015914.6
• Molecular Weight: 30,375 Da
• NCBI Official Full Name: thioredoxin domain-containing protein 11 isoform 2
• NCBI Official Synonym Full Names: thioredoxin domain containing 11
• NCBI Official Symbol: TXNDC11
• NCBI Official Synonym Symbols: EFP1
• NCBI Protein Information: thioredoxin domain-containing protein 11
• UniProt Protein Name: Thioredoxin domain-containing protein 11
• Protein Family: Thioredoxin domain-containing protein
• UniProt Gene Name: TXNDC11
• UniProt Synonym Gene Names: EFP1
• UniProt Entry Name: TXD11_HUMAN

Uniprot Description

TXNDC11: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein binding; protein disulfide isomerase activity

Biological Process: cell redox homeostasis; protein folding