NOVA1 blocking peptide

NOVA1 Immunizing Peptide

Cat. Num. AAA425688

• Gene Names: NOVA1; Nova-1
• Reactivity: Human
• Synonyms: NOVA1; NOVA1 Immunizing Peptide; neuro-oncological ventral antigen 1; Nova-1; paraneoplastic Ri antigen; ventral neuron-specific protein 1; NOVA1 blocking peptide

• Reactivity: Human
• Form/Format: 100ug of dried peptide
• Sequence: C-REMPQNVAKTEPVS
• Sequence Length: 507

• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 56549653
• NCBI GeneID: 4857
• NCBI Accession #: NP_002506.2; NP_006480.2; NP_006482.1
• NCBI GenBank Nucleotide #: NM_002515.2
• Molecular Weight: 49,253 Da
• NCBI Official Full Name: RNA-binding protein Nova-1 isoform 1
• NCBI Official Synonym Full Names: NOVA alternative splicing regulator 1
• NCBI Official Symbol: NOVA1
• NCBI Official Synonym Symbols: Nova-1
• NCBI Protein Information: RNA-binding protein Nova-1
• UniProt Protein Name: RNA-binding protein Nova-1
• Protein Family: RNA-binding protein
• UniProt Gene Name: NOVA1
• UniProt Entry Name: NOVA1_HUMAN

NCBI Description

This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

NOVA1: May regulate RNA splicing or metabolism in a specific subset of developing neurons. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 14q

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: mRNA binding; RNA binding

Biological Process: locomotory behavior; nuclear mRNA splicing, via spliceosome; regulation of mRNA processing; RNA processing; RNA splicing; spinal cord development; synaptic transmission