MPRIP blocking peptide
MPRIP Peptide - N-terminal region
Gene Names
MPRIP; MRIP; RIP3; M-RIP; RHOIP3; p116Rip
Reactivity
Human
Synonyms
MPRIP; MPRIP Peptide - N-terminal region; MPRIP blocking peptide
Reactivity
Human
Form/Format
Lyophilized powder
Sequence
Synthetic peptide located within the following region: RTNKQNQKKKRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTT
Sequence Length
1000
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Related Product Information for MPRIP blocking peptide
This is a synthetic peptide designed for use in combination with anti- MPRIP Antibody, made
Target Description: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
Target Description: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
Product Categories/Family for MPRIP blocking peptide
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
110 kDa
NCBI Official Full Name
myosin phosphatase Rho-interacting protein isoform 1
NCBI Official Synonym Full Names
myosin phosphatase Rho interacting protein
NCBI Official Symbol
MPRIP
NCBI Official Synonym Symbols
MRIP; RIP3; M-RIP; RHOIP3; p116Rip
NCBI Protein Information
myosin phosphatase Rho-interacting protein
UniProt Protein Name
Myosin phosphatase Rho-interacting protein
Protein Family
UniProt Gene Name
MPRIP
UniProt Synonym Gene Names
KIAA0864; MRIP; RHOIP3; M-RIP; RIP3
UniProt Entry Name
MPRIP_HUMAN
Uniprot Description
RIP3: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton
Molecular Function: protein binding; actin binding
Research Articles on MPRIP
Similar Products
Product Notes
The MPRIP mprip (Catalog #AAA3247628) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The MPRIP Peptide - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: Synthetic peptide located within the following region: RTNKQNQKKK RKVEPPTPQE PGPAKVAVTS SSSSSSSSSS IPSAEKVPTT. It is sometimes possible for the material contained within the vial of "MPRIP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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