CCRL1 blocking peptide
CCRL1 Peptide - C-terminal region
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]
Uniprot Description
CCRL1: Receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 3q22
Cellular Component: recycling endosome; integral to plasma membrane; early endosome; plasma membrane
Molecular Function: protein binding; chemokine receptor activity; chemokine binding; scavenger receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; receptor-mediated endocytosis; immune response; chemotaxis