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Western Blot (WB) (Western blot analysis of extracts from COLO cells, using SPTB2 antibody.)

anti-Human SPTB2 Antibody | anti-SPTB2 antibody

SPTB2 Antibody

Gene Names
SPTBN1; ELF; SPTB2; HEL102; betaSpII
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SPTB2; SPTB2 Antibody; beta-II spectrin; fodrin beta; SPCO_HUMAN; spectrin; non-erythroid beta 1; spectrin-beta II; anti-SPTB2 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
SPTB2 antibody detects endogenous levels of total SPTB2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
2364
Applicable Applications for anti-SPTB2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human SPTB2.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from COLO cells, using SPTB2 antibody.)

Western Blot (WB) (Western blot analysis of extracts from COLO cells, using SPTB2 antibody.)
References
Hu R.J., J. Biol. Chem. 267:18715-18722(1992). Chen Y., J. Mol. Neurosci. 17:59-70(2001). Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
251,397 Da
NCBI Official Full Name
spectrin beta chain, non-erythrocytic 1 isoform 1
NCBI Official Synonym Full Names
spectrin beta, non-erythrocytic 1
NCBI Official Symbol
SPTBN1
NCBI Official Synonym Symbols
ELF; SPTB2; HEL102; betaSpII
NCBI Protein Information
spectrin beta chain, non-erythrocytic 1
UniProt Protein Name
Spectrin beta chain, non-erythrocytic 1
UniProt Gene Name
SPTBN1
UniProt Synonym Gene Names
SPTB2

NCBI Description

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

Research Articles on SPTB2

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Product Notes

The SPTB2 sptbn1 (Catalog #AAA8509950) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SPTB2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPTB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the SPTB2 sptbn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPTB2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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