anti-Human PTGR1 Antibody | anti-PTGR1 antibody

PTGR1 Antibody

Cat. Num. AAA8514921

• Gene Names: PTGR1; PGR1; ZADH3; LTB4DH
• Reactivity: Human
• Applications: Western Blot
• Purity: Immunogen affinity purified
• Synonyms: PTGR1; PTGR1 Antibody; Prostaglandin reductase 1; PRG-1; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; EC=1.3.1.74; 15-oxoprostaglandin 13-reductase; EC=1.3.1.48; LTB4DH; anti-PTGR1 antibody

• Reactivity: Human
• Specificity: PTGR1 Antibody detects endogenous levels of total PTGR1
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 329

• Applicable Applications for anti-PTGR1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Preparation and Storage: Store at-20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from HT-29 cells, using PTGR1 antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 226059159
• NCBI GeneID: 22949
• NCBI Accession #: NP_001139580.1
• NCBI GenBank Nucleotide #: NM_001146108.1
• UniProt Accession #: Q14914; Q8IYQ0; Q9H1X6; A8K0N2; B4DPK3; F5GY50
• Molecular Weight: 36 KD
• NCBI Official Full Name: prostaglandin reductase 1 isoform 1
• NCBI Official Synonym Full Names: prostaglandin reductase 1
• NCBI Official Symbol: PTGR1
• NCBI Official Synonym Symbols: PGR1; ZADH3; LTB4DH
• NCBI Protein Information: prostaglandin reductase 1
• UniProt Protein Name: Prostaglandin reductase 1
• Protein Family: Prostaglandin reductase
• UniProt Gene Name: PTGR1
• UniProt Synonym Gene Names: LTB4DH; PRG-1

NCBI Description

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Uniprot Description

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.