anti-Human PHKG1 Antibody | anti-PHKG1 antibody

PHKG1 Antibody

Cat. Num. AAA8515491

• Gene Names: PHKG1; PHKG
• Reactivity: Human
• Applications: Western Blot
• Purity: Immunogen affinity purified
• Synonyms: PHKG1; PHKG1 Antibody; KPBG; PHKG; Phosphorylase B kinase gamma catalytic chain skeletal muscle isoform; Phosphorylase kinase gamma subunit 1; anti-PHKG1 antibody

• Reactivity: Human
• Specificity: PHKG1 Antibody detects endogenous levels of total PHKG1
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 419

• Applicable Applications for anti-PHKG1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Preparation and Storage: Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from HuvEc cells and HepG2 cells, using PHKG1 antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 386642885
• NCBI GeneID: 5260
• NCBI Accession #: NP_001245388.1
• NCBI GenBank Nucleotide #: NM_001258459.1
• UniProt Accession #: Q16816; Q75LP5; B7Z1D0; F5H2S1
• Molecular Weight: 45 KD
• NCBI Official Full Name: phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform 1
• NCBI Official Synonym Full Names: phosphorylase kinase catalytic subunit gamma 1
• NCBI Official Symbol: PHKG1
• NCBI Official Synonym Symbols: PHKG
• NCBI Protein Information: phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
• UniProt Protein Name: Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
• Protein Family: Phosphorylase b kinase
• UniProt Gene Name: PHKG1
• UniProt Synonym Gene Names: PHKG; PHK-gamma-M

NCBI Description

This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Uniprot Description

Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 ().