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Western Blot (WB) (Western blot analysis of lysate from 293T cell line,using CDK5RAP3 Antibody(MBS9200734). MBS9200734 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.)

Rabbit CDK5RAP3 Polyclonal Antibody | anti-CDK5RAP3 antibody

CDK5RAP3 Antibody

Gene Names
CDK5RAP3; C53; IC53; LZAP; HSF-27; MST016; PP1553; OK/SW-cl.114
Reactivity
Human, mouse, rat
Applications
Western Blot, ELISA
Purity
Affinity-Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CDK5RAP3; Polyclonal Antibody; CDK5RAP3 Antibody; CDK5 regulatory subunit-associated protein 3; CDK5 activator-binding protein C53; Protein HSF-27; IC53; anti-CDK5RAP3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Purity/Purification
Affinity-Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Positions
350-379
Sequence Length
531
Applicable Applications for anti-CDK5RAP3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:500
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of lysate from 293T cell line,using CDK5RAP3 Antibody(MBS9200734). MBS9200734 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.)

Western Blot (WB) (Western blot analysis of lysate from 293T cell line,using CDK5RAP3 Antibody(MBS9200734). MBS9200734 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.)
Related Product Information for anti-CDK5RAP3 antibody
Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1 (By similarity).
Product Categories/Family for anti-CDK5RAP3 antibody
References
Chen J.,et al.Biochem. Biophys. Res. Commun. 294:161-166(2002).
Xie Y.H.,et al.Cell Res. 13:83-91(2003).
Favier A.-L.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56921
NCBI Official Full Name
CDK5 regulatory subunit-associated protein 3 isoform c
NCBI Official Synonym Full Names
CDK5 regulatory subunit associated protein 3
NCBI Official Symbol
CDK5RAP3
NCBI Official Synonym Symbols
C53; IC53; LZAP; HSF-27; MST016; PP1553; OK/SW-cl.114
NCBI Protein Information
CDK5 regulatory subunit-associated protein 3
UniProt Protein Name
CDK5 regulatory subunit-associated protein 3
Protein Family
UniProt Gene Name
CDK5RAP3
UniProt Entry Name
CK5P3_HUMAN

NCBI Description

This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]

Uniprot Description

CDK5RAP3: Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1. Belongs to the CDK5RAP3 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: protein complex; membrane; cytoplasm; nucleolus; endomembrane system; nucleus

Molecular Function: cyclin binding; protein binding; protein kinase binding

Biological Process: cell proliferation; positive regulation of protein ubiquitination; inhibition of NF-kappaB transcription factor; regulation of neuron differentiation; regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; regulation of cyclin-dependent protein kinase activity; brain development

Research Articles on CDK5RAP3

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Product Notes

The CDK5RAP3 cdk5rap3 (Catalog #AAA9200734) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 350-379. The CDK5RAP3 Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDK5RAP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:500. Researchers should empirically determine the suitability of the CDK5RAP3 cdk5rap3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK5RAP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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