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Testing Data (PARP1(ASP214)antibody (E230015) at 1/5000 dilution interacts with 293T whole cell lysate 40ug/Lane. Predicted band size: 113KDa. Observed band size: 113KDa. Additional band size: 70KDa.)

anti-Human PARP1 Antibody | anti-PARP1 antibody

PARP1 Antibody

Gene Names
PARP11; ARTD11; MIB006; C12orf6
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Protein G-Sepharose affinity purified.
Synonyms
PARP1; PARP1 Antibody; anti-PARP1 antibody
Ordering
For Research Use Only!
Reactivity
Human
Purity/Purification
Protein G-Sepharose affinity purified.
Form/Format
Liquid
Sequence Length
338
Applicable Applications for anti-PARP1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:5000-1:20000
WB: 1:5000-1:10000
Immunogen
Synthetic peptide corresponding to N-terminus amino acids of PARP1 human protein.
Preservative
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.

Testing Data

(PARP1(ASP214)antibody (E230015) at 1/5000 dilution interacts with 293T whole cell lysate 40ug/Lane. Predicted band size: 113KDa. Observed band size: 113KDa. Additional band size: 70KDa.)

Testing Data (PARP1(ASP214)antibody (E230015) at 1/5000 dilution interacts with 293T whole cell lysate 40ug/Lane. Predicted band size: 113KDa. Observed band size: 113KDa. Additional band size: 70KDa.)
Related Product Information for anti-PARP1 antibody
PARP (Poly (ADP-ribose) polymerase) is a 113 kDa nuclear protein which can exist as a homo-or hetero-dimer, and is strongly activated by DNA strand breaks. This protein acts as a molecular "nick sensor" and functions in base excision repair, poly(ADPribosyl)ation of acceptor proteins involved in chromatin architecture and DNA metabolism, and participates in protein modification to enhance or repress transcription. PARP also plays a role in other cellular processes, including cell proliferation and differentiation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,098 Da
NCBI Official Full Name
poly
NCBI Official Synonym Full Names
poly(ADP-ribose) polymerase family member 11
NCBI Official Symbol
PARP11
NCBI Official Synonym Symbols
ARTD11; MIB006; C12orf6
NCBI Protein Information
poly [ADP-ribose] polymerase 11
UniProt Protein Name
Poly [ADP-ribose] polymerase 11
UniProt Gene Name
PARP11
UniProt Synonym Gene Names
C12orf6; PARP-11; ARTD11

Uniprot Description

Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (). In vitro, exhibits mono(ADP-ribosyl) transferase activity (PubMed:25673562).

Research Articles on PARP1

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Product Notes

The PARP1 parp11 (Catalog #AAA8504513) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PARP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PARP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:5000-1:20000 WB: 1:5000-1:10000. Researchers should empirically determine the suitability of the PARP1 parp11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARP1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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