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Testing Data

anti-Human KCNJ5 Antibody | anti-KCNJ5 antibody

KCNJ5 Antibody

Gene Names
KCNJ5; CIR; GIRK4; KATP1; LQT13; KIR3.4
Reactivity
Human
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
KCNJ5; KCNJ5 Antibody; Cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; Heart KATP channel; Inward rectifier K channel Kir3.4; IRK5; KATP-1; Kir3.4; Potassium channel; inwardly rectifying; subfamily J; member 5; anti-KCNJ5 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
KCNJ5 antibody detects endogenous levels of total KCNJ5 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
419
Applicable Applications for anti-KCNJ5 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of humanKCNJ5.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data

Western Blot (WB)

(Peptide-+ Western blot analysis of extracts from HeLa cells, using KCNJ5 antibody. Immunofluorescence analysis of A549 cells, using KCNJ5 antibody.)

Western Blot (WB) (Peptide-+ Western blot analysis of extracts from HeLa cells, using KCNJ5 antibody. Immunofluorescence analysis of A549 cells, using KCNJ5 antibody.)
References
Ashford M.L.J., Nature 370:456-459(1994). Ashford M.L.J., Nature 378:792-792(1995). Schoots O., Cell. Signal. 11:871-883(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,668 Da
NCBI Official Full Name
G protein-activated inward rectifier potassium channel 4
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily J member 5
NCBI Official Symbol
KCNJ5
NCBI Official Synonym Symbols
CIR; GIRK4; KATP1; LQT13; KIR3.4
NCBI Protein Information
G protein-activated inward rectifier potassium channel 4
UniProt Protein Name
G protein-activated inward rectifier potassium channel 4
UniProt Gene Name
KCNJ5
UniProt Synonym Gene Names
GIRK4; GIRK-4; CIR; IRK-4

NCBI Description

This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]

Uniprot Description

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Research Articles on KCNJ5

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Product Notes

The KCNJ5 kcnj5 (Catalog #AAA8510003) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The KCNJ5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNJ5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000. Researchers should empirically determine the suitability of the KCNJ5 kcnj5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNJ5, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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