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Testing Data

anti-Human IL11RA Antibody | anti-IL11RA antibody

IL11RA Antibody

Gene Names
IL11RA; CRSDA
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
IL11RA; IL11RA Antibody; Interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; anti-IL11RA antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
IL11RA antibody detects endogenous levels of total IL11RA protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
422
Applicable Applications for anti-IL11RA antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:3000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human IL11RA.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data
References
Cherel M., Blood 86:2534-2540(1995). Van Leuven F., Genomics 31:65-70(1996). Kalnine N., Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,842 Da
NCBI Official Full Name
interleukin-11 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 11 receptor subunit alpha
NCBI Official Symbol
IL11RA
NCBI Official Synonym Symbols
CRSDA
NCBI Protein Information
interleukin-11 receptor subunit alpha
UniProt Protein Name
Interleukin-11 receptor subunit alpha
Protein Family
UniProt Gene Name
IL11RA
UniProt Synonym Gene Names
IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA

NCBI Description

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Uniprot Description

Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Research Articles on IL11RA

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Product Notes

The IL11RA il11ra (Catalog #AAA858175) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The IL11RA Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL11RA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:3000 ELISA: 1:20000. Researchers should empirically determine the suitability of the IL11RA il11ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL11RA, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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