Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CEP110 antibody.)
anti-Human CEP110 Antibody | anti-CEP110 antibody
CEP110 Antibody
Gene Names
CCP110; CP110; Cep110
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CEP110; CEP110 Antibody; CENTRIOLIN; centrosomal protein 110kDa; CEP1; FAN; anti-CEP110 antibody
Reactivity
Human
Specificity
CEP110 antibody detects endogenous levels of total CEP110 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1012
Applicable Applications for anti-CEP110 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:40000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CEP110.
Preparation and Storage
Store at-20 degree C for 1 year.
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CEP110 antibody.)
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CEP110 antibody.)
Product Categories/Family for anti-CEP110 antibody
References
Martin J., Nature 432:988-994(2004). Chen Z., Dev. Cell 3:339-350(2002). Andersen J.S., Nature 426:570-574(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
111,224 Da
NCBI Official Full Name
centriolar coiled-coil protein of 110 kDa isoform 1
NCBI Official Synonym Full Names
centriolar coiled-coil protein 110
NCBI Official Symbol
CCP110
NCBI Official Synonym Symbols
CP110; Cep110
NCBI Protein Information
centriolar coiled-coil protein of 110 kDa
UniProt Protein Name
Centriolar coiled-coil protein of 110 kDa
UniProt Gene Name
CCP110
UniProt Synonym Gene Names
CEP110; CP110; KIAA0419; CP110; Cep110
Uniprot Description
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Research Articles on CEP110
Similar Products
Product Notes
The CEP110 ccp110 (Catalog #AAA859960) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CEP110 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CEP110 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the CEP110 ccp110 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEP110, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
