Immunohistochemistry (IHC)
(IHC staining of human colon cancer tissue with CEA mouse mAb(10E1) diluted at 1:200.)
anti-Human Carcinoembryonic Antigen (CEA) Antibody | anti-CEA antibody
Carcinoembryonic Antigen (CEA)Antibody
Gene Names
CEACAM5; CEA; CD66e
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Carcinoembryonic Antigen (CEA); Carcinoembryonic Antigen (CEA)Antibody; anti-CEA antibody
Reactivity
Human
Clone Number
10E1
Specificity
The CEA Mouse Monoclonal Antibody detects endogenous ~113KD CEA proteins.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
698
Applicable Applications for anti-CEA antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:200
Preparation and Storage
Store at-20 degree C for 1 year
Immunohistochemistry (IHC)
(IHC staining of human colon cancer tissue with CEA mouse mAb(10E1) diluted at 1:200.)
Immunohistochemistry (IHC)
(IHC staining of human colon cancer tissue with CEA mouse mAb(10E1) diluted at 1:200.)
Related Product Information for anti-CEA antibody
CEA is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
76,724 Da
NCBI Official Full Name
carcinoembryonic antigen, partial
NCBI Official Synonym Full Names
carcinoembryonic antigen related cell adhesion molecule 5
NCBI Official Symbol
CEACAM5
NCBI Official Synonym Symbols
CEA; CD66e
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 5
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 5
Protein Family
UniProt Gene Name
CEACAM5
UniProt Synonym Gene Names
CEA; CEA
NCBI Description
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Uniprot Description
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
Research Articles on CEA
Similar Products
Product Notes
The CEA ceacam5 (Catalog #AAA8527284) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Carcinoembryonic Antigen (CEA)Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Carcinoembryonic Antigen (CEA) can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:200. Researchers should empirically determine the suitability of the CEA ceacam5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Carcinoembryonic Antigen (CEA), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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